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> If you take a lot of aspirin.....
post Aug 6 2013, 07:12 AM
Post #1

Diabetical Pundit

Group: Moderator
Posts: 2,549
Joined: 7-February 08
From: Colorado
Member No.: 857
My Pump: mm 522

I was reading through the abstracts from the American Association of Clinical Endocrinologists, and read a really interesting one (there's actually a lot of them). This particular one was entitled 'Unusual Cause of Hypoglycemia in a Diabetic Patient - Salicylate Toxicity'.

It seems a 59 year old man was taken to the ER with "generalized seizures and hypoglycemia with a BG of 36 mg/dl". He was a type 2 diabetic "on insulin, and no other diabetic medications and had never had hypoglycemia before" (huh?!? - on insulin and never been hypo?).

The hypo was "attributed to insulin use. Insulin dose was decreased and patient was discharged home. Patient comes back again in two days with unresponsiveness and recurrent hypoglycemia despite decreasing insulin dose. He was admitted and insulin was discontinued. Next day he was mildly confused and disoriented ... and BG was 38 mg/dl which was corrected to 168 with IV dextrose. But, symptoms persisted for more than 2 hours..... Patient's last dose of insulin was more than 24 hours back."

The doctors returned to the patients room "to get more information and found several unmarked white pills at bedside, for which patient admitted to taking a handful of aspirin tablets a few hours earlier. Also, he has been taking at least 20-30 aspirin tablets daily for the last one month for peripheral neuropathy. Salicylate level was found to be 78 mg/dl (usual therapeutic range: 0-30 mg/dl)."

The authors conclude that "Salicylate toxicity should be considered in the differential diagnosis for unexplained hypoglycemia. Neuroglycopenia with normal blood glucose levels can occur".

I had to look up what neuroglycopenia is. Wikipedia says it refers to a shortage of glucose in the brain.

So...moral of the story: No matter how much you hurt, don't take 20-30 aspirins a day!


Forum moderator
LADA - dx'd 1985 at age 31 - treated as type 2
Insulin therapy in 1987
mm 522 since Aug. 2007, cgms since Nov. 2007
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post Aug 7 2013, 02:22 AM
Post #2

IPF Pundit

Group: Members
Posts: 779
Joined: 15-January 11
From: northern IL
Member No.: 3,436
My Pump: Tandem Tslim

It is a wonder the guy didn't bleed internally from taking so many aspirins.

Dexcom CGM - Sep 2007
Tandem Tslim - Oct 2015
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Mrs O
post Aug 8 2013, 01:06 PM
Post #3

IPF Regular

Group: Members
Posts: 159
Joined: 25-January 12
From: Somerset, UK
Member No.: 4,068
My Pump: Accu Chek Combo

I am amazed he didn't rattle!!
Self prescribing is always a dodgy route to venture down.

Type 1 Diabetic, diagnosed at 2 years old on 1st August 1976.
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